abstract：:Neutral glycolipids (NGL) are promising diagnostic markers of human gliomas, but differences in NGL with age and sex have not been examined. Previous work demonstrated that ceramide dihexosides (CDH) levels in mouse kidney are age- and sex-dependent, probably due to levels of sex hormones. We quantitated CDH in 181 hu...

journal_title：Lipids

authors： Yates AJ,Franklin TK,Scheithauer BW,Burger PC,Pearl DK

更新日期：1999-01-01 00:00:00

abstract：:The present studies tested the hypothesis that some effects of tumor necrosis factor-alpha (TNF-alpha) are mediated by activation of sphingomyelinases and the production of ceramides. Differentiated 3T3-L1 adipocytes were incubated with short-chain ceramide analogs, (C2- and C6-ceramides: N-acetyl- and N-hexanoyl-sphi...

journal_title：Lipids

authors： Brindley DN,Wang CN,Mei J,Xu J,Hanna AN

更新日期：1999-01-01 00:00:00

abstract：:All fatty acids have important functions, but the term "essential" is applied only to those polyunsaturated fatty acids (PUFA) that are necessary for good health and cannot be completely synthesized in the body. The need for arachidonic acid, which is utilized for eicosanoid synthesis and is a constituent of membrane ...

journal_title：Lipids

authors： Spector AA

更新日期：1999-01-01 00:00:00

abstract：:An increased amount of phospholipids remained attached on delipidated apolipoprotein B originated from oxidized low density lipoprotein (LDL). 31P nuclear magnetic resonance analysis of such apolipoprotein showed an organic phosphorus peak at -0.55 ppm, which suggests the formation of adducts (most probably Schiff bas...

journal_title：Lipids

authors： Karakatsani AI,Liapikos TA,Troganis AN,Tsoukatos DC

更新日期：1998-12-01 00:00:00

abstract：:Saccharomyces cerevisiae cells were demonstrated to contain lysophosphatidylcholine (lysoPtdCho) acyltransferase (E.C. 2.3.1.23) activity. The enzyme displayed Km(app) of 69 microM for lysoPtdCho and 152 microM for oleoyl CoA. Enzyme activity was not affected by the addition of 1 mM Mg2+, Mn2+, Ca2+, or 200 mM EDTA. H...

journal_title：Lipids

authors： Richard MG,McMaster CR

更新日期：1998-12-01 00:00:00

abstract：:Concentrations of synthetic antioxidants butylated hydroxyanisole, butylated hydroxytoluene, and tert-butyl hydroquinone were quantified using a high-performance liquid chromatograph with spectrofluorometric detector. The antioxidants were separated and eluted on a reversed-phase column by gradient of a mixture of H2O...

journal_title：Lipids

authors： Yankah VV,Ushio H,Ohshima T,Koizumi C

更新日期：1998-11-01 00:00:00

abstract：:[1-14C]alpha-Linolenic acid was incubated with a particulate fraction of homogenate of leaves of the meadow buttercup (Ranunculus acris L.). The main product was a divinyl ether fatty acid, which was identified as 12-[1'(Z),3'(Z)-hexadienyloxy]-9(Z),11(E)-dodecadienoic acid. Addition of glutathione peroxidase and redu...

journal_title：Lipids

authors： Hamberg M

更新日期：1998-11-01 00:00:00

abstract：:The purpose of the present investigation was to test whether permanent skeletal muscle cells (rat L6 cells) could serve as an in vitro model for alpha-tocopherol (alphaTocH) biodiscrimination studies. L6 cells were incubated in the presence of high density lipoprotein (HDL), low density lipoprotein (LDL), and very low...

journal_title：Lipids

authors： Nakamura T,Reicher H,Sattler W

更新日期：1998-10-01 00:00:00

abstract：:Salmon farmers are currently using high-energy feeds containing up to 35% fat; the fish's capability of fully utilizing these high-energy feeds has received little attention. Carnitine is an essential component in the process of mitochondrial fatty acid oxidation and, with the cooperation of two carnitine palmitoyltra...

journal_title：Lipids

authors： Frøyland L,Madsen L,Eckhoff KM,Lie O,Berge RK

更新日期：1998-09-01 00:00:00

abstract：:The relationship between the biosynthesis of long-chain fatty acids and their distribution in the key organs of hypertension is of considerable interest because of their role in the production of vasoactive eicosanoids and their effects on membrane properties. The present study analyzed the fatty acid compositions of ...

journal_title：Lipids

authors： Delachambre MC,Narce M,Asdrubal P,Poisson JP

更新日期：1998-08-01 00:00:00

abstract：:This study was conducted to investigate the effects of dietary cyclic fatty acid monomers (CFAM), contained in heated fat from a commercial deep-fat frying operation, on rat liver enzyme activity. A partially hydrogenated soybean oil (PHSBO) used 7 d (7-DH) for frying foodstuffs, or 0.15% methylated CFAM diets was fed...

journal_title：Lipids

authors： Lamboni C,Sébédio JL,Perkins EG

更新日期：1998-07-01 00:00:00

abstract：:Epoxidation of the double bond in methyl oleate, octadec-11E-en-9-ynoate, ricinoleate (12-hydroxy-octadec-9Z-enoate), iso-ricinoleate (9-hydroxy-octadec-12Z-enoate), and 12-oxo-octadec-9Z-enoate with potassium peroxomonosulfate (oxone, 2 KHSO5.KHSO4.K2SO4) in the presence of trifluoroacetone or methyl pyruvate gave th...

journal_title：Lipids

authors： Lie Ken Jie MS,Pasha MK

更新日期：1998-06-01 00:00:00

abstract：:The purpose of this study was to examine the effect of dietary docosahexaenoic acid (DHA), in the absence of eicosapentaenoic acid, on human immune response (IR). A 120-d study with 11 healthy men was conducted at the Metabolic Research Unit of the Western Human Nutrition Research Center. Four subjects (control group)...

journal_title：Lipids

authors： Kelley DS,Taylor PC,Nelson GJ,Mackey BE

更新日期：1998-06-01 00:00:00

abstract：:The effects of conjugated linoleic acid (CLA) on the levels of chemical mediators in peritoneal exudate cells, spleen and lung, and the concentration of immunoglobulins in mesenteric lymph node and splenic lymphocytes and in serum were examined in rats. After feeding diets containing either 0 (control), 0.5 or 1.0% CL...

journal_title：Lipids

authors： Sugano M,Tsujita A,Yamasaki M,Noguchi M,Yamada K

更新日期：1998-05-01 00:00:00

abstract：:This study evaluated the effects of conjugated linoleic acids (CLA) on tissue fatty acid composition and ex vivo prostaglandin E2 (PGE2) production in rats given diets varying in n-6 and n-3 fatty acids. Four groups of rats were given a basal semipurified diet (AIN-93G) containing 70 g/kg of added fat for 42 d. The fa...

journal_title：Lipids

authors： Li Y,Watkins BA

更新日期：1998-04-01 00:00:00

abstract：:This study compared (i) the relative effects of long-chain triglycerides (LCT) and medium-chain triglycerides (MCT), (ii) the influence of amount of MCT, and (iii) the impact of medium-chain fatty acid position, on plasma and lymphatic triglycerides and portal vein free fatty acids. The animals were fed approximately ...

journal_title：Lipids

authors： You YQ,Ling PR,Qu Z,Bistrian BR

更新日期：1998-03-01 00:00:00

abstract：:We have developed cultures of smooth muscle cells (SMC) isolated from arterial hypercholesterolemic chicks (cholesterol-SMC). These cultures are suitable for the study at the molecular level of the changes in arterial SMC induced by a cholesterol diet. By using a strong dose of cholesterol (5%) for 10 d, we obtained v...

journal_title：Lipids

authors： Carazo A,Alejandre J,Diaz R,Ríos A,Castillo M,Linares A

更新日期：1998-02-01 00:00:00

abstract：:In the wild, nutrients from plants provide for the requirements of all herbivores and ultimately all animals, yet little work has been published on how such nutrients change with environmental conditions. Plant lipids are nutritionally important for browsing mammals, initially with respect to taste and palatability, b...

journal_title：Lipids

authors： Davidson BC

更新日期：1998-01-01 00:00:00

abstract：:Studies investigated the effects of dietary fatty acid composition and saturation on the regulation of very low density lipoprotein (VLDL) apo B flux, clearance, and conversion to low density lipoprotein (LDL) in guinea pigs fed semipurified diets containing 15% (w/w) corn oil (CO), lard (LA), or palm kernel oil (PK)....

journal_title：Lipids

authors： Abdel-Fattah G,Fernandez ML,McNamara DJ

更新日期：1998-01-01 00:00:00

abstract：:A protocol, based on the use of Pseudomonas lipase, is presented to measure quantitatively the amount of triacylglycerols in extracts from cultured cells of tissues. Since the lipase also acts on di- and monoacylglycerols, separation of the extracts by thin-layer chromatography is recommended. In order to allow the li...

journal_title：Lipids

authors： Van Veldhoven PP,Swinnen JV,Esquenet M,Verhoeven G

更新日期：1997-12-01 00:00:00

abstract：:Adipocere formation is well known as a later postmortem change. We collected adipocere from five male victims which had been submerged under the sea or fresh water for 1 mon to 4 yr. Fresh subcutaneous fat of a male victim who died from a cerebral contusion was used as the control. The samples were homogenized, and th...

journal_title：Lipids

authors： Adachi J,Ueno Y,Miwa A,Asano M,Nishimura A,Tatsuno Y

更新日期：1997-11-01 00:00:00

abstract：:The growth inhibitory effects of 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine (ET-18-OCH3) and various liposome compositions of ET-18-OCH3 were compared in a standardized growth inhibition assay utilizing a diverse tumor cell line panel including cell lines expressing multidrug resistance. ET-18-OCH3 and ELL-1...

journal_title：Lipids

authors： Peters AC,Ahmad I,Janoff AS,Pushkareva MY,Mayhew E

更新日期：1997-10-01 00:00:00

abstract：:An unidentified bacterial strain, SCRC-21406, isolated from the intestine of a marine fish, Glossanodon semifasciatus, produced docosahexaenoic acid at 23% (mol/mol) [= 28% (w/w)] of total fatty acids in a medium containing 0.5% (wt/vol) peptone and 0.1% (wt/vol) yeast extract at 12 degrees C under atmospheric pressur...

journal_title：Lipids

authors： Watanabe K,Ishikawa C,Ohtsuka I,Kamata M,Tomita M,Yazawa K,Muramatsu H

更新日期：1997-09-01 00:00:00

abstract：:Competitive inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase improve hypercholesterolemia. However, reports about the effects of these agents on bile acid synthesis, the metabolic pathway of cholesterol, are conflicting. We studied the short-term effect on one of these agents, pravastatin, on bile acid synthesis...

journal_title：Lipids

authors： Yoshida T,Honda A,Shoda J,Abei M,Matsuzaki Y,Tanaka N,Miyazaki H,Osuga T

更新日期：1997-08-01 00:00:00

abstract：:A 10-hydroxy stearic acid-containing lipid from Cryptosporidium parvum was purified by thin-layer chromatography and analyzed by infrared spectroscopy, fast-atom bombardment mass spectrometry, 1H and 31P nuclear magnetic resonance spectroscopy, and was identified as phosphatidyl-ethanolamine. ...

journal_title：Lipids

authors： Schrum DP,Alugupalli S,Kelly ST,White DC,Fayer R

更新日期：1997-07-01 00:00:00

abstract：:Recent work in our lab has shown that the chemoprotective fatty acid, conjugated linoleic acid (CLA), inhibits phorbol ester skin tumor promotion in mice. Because little is known about the deposition of CLA into tissues as well as its biological activity, this study compared the incorporation and biological activity o...

journal_title：Lipids

authors： Liu KL,Belury MA

更新日期：1997-07-01 00:00:00

abstract：:Hepatocytes isolated from rainbow trout fed on diets containing either fish oil or olive oil were incubated with individual odd-chain length unsaturated fatty acids (19:1n-9, 19:2n-6, 19:3n-3, 21:2n-6, 21:3n-6, 21:4n-6, 21:3n-3, and 21:5n-3) to examine whether these fatty acids were substrates for modification by desa...

journal_title：Lipids

authors： Rodríguez C,Henderson RJ,Porter AE,Dick JR

更新日期：1997-06-01 00:00:00

abstract：:The purpose of this study was to investigate in healthy humans the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intake, alone or in combination with dL-alpha-tocopherol acetate (vitamin E) supplements on lipid peroxidation. Eighty men were randomly assigned in a double-blind fashion to take dai...

journal_title：Lipids

authors： Allard JP,Kurian R,Aghdassi E,Muggli R,Royall D

更新日期：1997-05-01 00:00:00

abstract：:While there are many reports of studies that fed arachidonic acid (AA) to animals, there are very few reports of AA feeding to humans under controlled conditions. This 130-d study was conceived as a controlled, symmetrical crossover design with healthy, adult male volunteers. They lived in the metabolic research unit ...

journal_title：Lipids

authors： Nelson GJ,Kelley DS,Emken EA,Phinney SD,Kyle D,Ferretti A

更新日期：1997-04-01 00:00:00

abstract：:This paper describes a simple method for the analysis of tocopherols in tissues by which frozen tissues-70 degrees C were pulverized at dry ice temperatures (-70 degrees C) and immediately extracted with hexane. There was no need to remove the coeluting lipids from tissues by saponification, since at that level of neu...

journal_title：Lipids

authors： Kramer JK,Blais L,Fouchard RC,Melnyk RA,Kallury KM

更新日期：1997-03-01 00:00:00

abstract：:The monoazaaromatics, pyridine (1), hexyl nicotinate (2), and quinoline (3) and diazaaromatics, pyrimidine (4) and purine (5), readily act as photo-initiators for the peroxidation of methyl linoleate in 0.50 M SDS at 37 degrees C giving free radical chain oxidations of linoleate. Quantitative kinetic runs on the order...

journal_title：Lipids

authors： Barclay LR,Crowe E,Edwards CD

更新日期：1997-03-01 00:00:00

abstract：:The fatty acid composition of the membrane phospholipids phosphatidylcholine (PC) and phosphatidylethanolamine in insulin-sensitive Type I (soleus) and insulin-resistant Type II (EDL) muscle is not known. In the present studies, soleus and EDL muscles were removed from 250-300 g Sprague-Dawley rats, and the fatty acid...

journal_title：Lipids

authors： Blackard WG,Li J,Clore JN,Rizzo WB

更新日期：1997-02-01 00:00:00

abstract：:To test the effects of eicosapentaenoic acid (EPA) infusion on pulmonary edema induced by coronary ligation and reperfusion, extravascular lung water (EVLW) was measured in situ by the thermal-dye double indicator dilution method in dogs. In the control group of five dogs, 30 mL of a 10% soybean oil emulsion was infus...

journal_title：Lipids

authors： Izuoka T,Kimura Y,Hamazaki T,Tamura T,Kitashiro S,Sugiura T,Jikuhara T,Iwasaka T

更新日期：1997-01-01 00:00:00

abstract：:The influence of diet on the kinetics of the overt form of rat liver mitochondrial carnitine palmitoyltransferase (CPT I; EC 2.3.1.21) was studied using rats fed either a low-fat diet (3% w/w fat), or diets which were supplemented with either olive oil (OO), safflower oil (SO) or menhaden (fish) oil (MO) to 20% w/w of...

journal_title：Lipids

authors： Power GW,Cake MH,Newsholme EA

更新日期：1997-01-01 00:00:00

abstract：:Using primary rat hepatocyte cultures, the potency of several garlic-derived organosulfur compounds to inhibit cholesterol biosynthesis in toto as well as at early and late steps of this metabolic pathway was compared. Concerning early steps, allicin significantly inhibited incorporation of [14C]acetate into nonsaponi...

journal_title：Lipids

authors： Gebhardt R,Beck H

更新日期：1996-12-01 00:00:00

abstract：:The effects of growth temperature on the fatty acid compositions of the phosphatidylcholine (PC), phosphatidylethanolamine (PE), and total lipid (TL) fractions of the free-living nematode Caenorhabditis elegans were investigated. A reduction in growth temperature from 25 to 15 degrees C caused the proportions of eicos...

journal_title：Lipids

authors： Tanaka T,Ikita K,Ashida T,Motoyama Y,Yamaguchi Y,Satouchi K

更新日期：1996-11-01 00:00:00

abstract：:In the present paper, problems in connection with assay of the activity of magnesium-dependent rat liver phosphatidate phosphohydrolase (PAP) are discussed. PAP activity is usually measured by following the production of diacylglycerol or inorganic phosphate from the substrate phosphatidate. These two methods may give...

journal_title：Lipids

authors： Stark M,Humble E

更新日期：1996-10-01 00:00:00

abstract：:Treatment of (13S,9Z,11E)-13-hydroperoxy-9,11-octadecadienoic acid (13S-HPODE) with strong alkali resulted in the formation of about 75% of the corresponding hydroxy acid, (13S,9Z,11E)-13-hydroxy-9,11-octadecadienoic acid (13S-HODE), and the remaining 25% of products was a mixture of several oxidized fatty acids, the ...

journal_title：Lipids

authors： Gardner HW,Simpson TD,Hamberg M

更新日期：1996-10-01 00:00:00

abstract：:In a detailed sterol analysis of the marine diatom Phaeodactylum tricornutum, free sterols as well as esterified and glycosylated conjugates were found. When the alga was grown under standard conditions (i.e., at 13 degrees C under white light), 64% of total sterols were steryl glycosides. In all sterol classes, excep...

journal_title：Lipids

authors： Véron B,Billard C,Dauguet JC,Hartmann MA

更新日期：1996-09-01 00:00:00

abstract：:The physiological role of long-chain fatty acyl-CoA is thought to be primarily in intermediary metabolism of fatty acids. However, recent data show that nM to microM levels of these lipophilic molecules are potent regulators of cell functions in vitro. Although long-chain fatty acyl-CoA are present at several hundred ...

journal_title：Lipids

authors： Gossett RE,Frolov AA,Roths JB,Behnke WD,Kier AB,Schroeder F

更新日期：1996-09-01 00:00:00